On June 17, 2026, Renaissance Investment Management unveiled its Q1 2026 investor letter for the Large‑Cap Growth Strategy. The letter chronicles a quarter in which U.S. equities fell sharply, largely because of escalating tensions between the United States and Iran. In that turbulent environment, the strategy’s portfolio posted a return that matched the S&P 500’s –4.3 % decline but still outpaced the Russell 1000 Growth Index, which slipped 9.8 %.

The letter’s sector‑level analysis reveals a clear pattern. Energy and Materials stocks emerged as the strongest performers, while Financials and Consumer Discretionary lagged. Among large‑cap equities, those with a value tilt outperformed the growth‑style holdings, underscoring the risk‑aversion that investors exhibited during the quarter. These dynamics mirror the broader market volatility triggered by geopolitical uncertainty.

Renaissance’s own figures highlight the strategy’s resilience. The portfolio’s return of –4.3 % exactly matched the S&P 500’s loss, yet it still eclipsed the broader decline seen in the Russell 1000 Growth Index. The letter notes that large‑cap stocks underperformed their smaller‑cap counterparts—a trend that may reflect heightened caution among investors amid the crisis.

A key highlight of the quarter was Boston Scientific Corporation (NYSE: BSX). The medical‑device company closed at $46.92 per share on June 16, 2026, following a one‑month decline of 17.20 % and a 53.71 % drop over the past year. Its market capitalization was reported at $69.74 billion. Renaissance pointed out that Boston Scientific’s share price fell after the company issued 2026 guidance that missed expectations, citing a slowdown in revenue growth within its electrophysiology segment. The letter suggested that the slowdown could signal that Medtronic, a major competitor, is gaining market share.

In hedge‑fund exposure terms, Renaissance noted that 110 hedge‑fund portfolios held Boston Scientific at the end of Q4 2026, up from 102 in the previous quarter. The company’s Q1 2026 consolidated revenue reached $5.203 billion, an 11.6 % year‑over‑year increase compared with Q1 2025.

Looking ahead, Renaissance highlighted artificial‑intelligence (AI) stocks as potentially offering greater upside potential and lower downside risk. The firm referenced a free report on a short‑term AI stock for readers.

In sum, Renaissance’s Large‑Cap Growth Strategy delivered a return that beat the S&P 500 during a quarter of heightened geopolitical risk, though it lagged the Russell 1000 Growth Index. Energy and Materials led the portfolio’s gains, while Financials and Consumer Discretionary underperformed. Boston Scientific remains a prominent holding, but its recent guidance and market performance have drawn attention. The firm continues to monitor risk factors and potential investment opportunities as the Iran conflict and broader market conditions evolve.